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PCK2 inhibits lung adenocarcinoma tumor cell immune escape through oxidative stress-induced senescence as a potential therapeutic target

1 May 2023

Abstract excerpt

Background: Our research aimed to better understand how phosphoenolpyruvate carboxykinase 2 ( PCK2 ) is linked to survival outcomes in lung cancer patients. Methods: We confirmed PCK2 expression and its association with the outcome of lung cancer patients using The Cancer Genome Atlas (TCGA) database. PCK2 and immune cell connections were investigated using data from the Tumor IMmune Estimation Resource (TIMER)...

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PMID: 37324064
DOI: 10.21037/jtd-23-542

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