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Sub-chronic exposure to diazinon induce cognitive impairment, alternations in amyloid precursor proteins, and TNF-α expression in the hippocampus of adult rats

2023-06-01

Abstract excerpt

Organophosphate pesticides such as diazinon (DZN) are involved in the development of psychological symptoms and memory deficits but their effects on the amyloid precursor proteins (APP) genes expression remains unclear. Following low-level oral exposure to the DZN (2 mg/kg), we used novel object recognition, open field, and elevated plus-mazes (EPM) to assess memory and anxiety-like behaviors in rats. We also eval...

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Literature Corpus work
4a690567-6388-537c-941a-d47d70f70ac4
DOI
10.21203/rs.3.rs-2987894/v1
Open publication

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Sub-chronic exposure to diazinon induce cognitive impairment, alternations in amyloid precursor proteins, and TNF-α expression in the hippocampus of adult ratsDOI 10.21203/rs.3.rs-2987894/v1
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