Article

A novel copper-sensing two-component system for activating Dsb genes in bacteria

2020-08-18

Abstract excerpt

Copper is an essential element for biological systems but becomes toxic when present in excess. In Pseudomonas aeruginosa , an important human pathogen, the resistance to copper requires the induction of dsbDEG operon encoding proteins involved in disulfide-bond formation (Dsb). However, it is unknown how the copper stress induces the transcription of the operon. Here, we report that the exogenous copper induces...

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Literature Corpus work: 4a381017-83b4-5bcd-b27b-490b5fd06ad5
DOI: 10.1101/2020.08.17.255257

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