Article

Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy

2018-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Super-resolution (SR) microscopy has been used to observe structural details beyond the diffraction limit of ~250 nm in a variety of biological and materials systems. By combining this imaging technique with both computer-vision algorithms and topological methods, we reveal and quantify the nanoscale morphology of the primary cilium, a tiny tubular cellular structure (~2-6 μm long and 200-300...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 49f01c92-5afc-5b0d-90a4-da1e1465ba46
DOI: 10.1101/437640

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopyDOI 10.1101/437640Read

A quantitative super-resolution imaging toolbox for diagnosis of motile ciliopathies.Semantic proximity Read

Defining the Layers of a Sensory Cilium with STORM and Cryo-Electron NanoscopiesSemantic proximity Read

Superresolution STED microscopy reveals differential localization in primary ciliaSemantic proximity Read

Super-resolution microscopy reveals that disruption of ciliary transition zone architecture is a cause of Joubert syndromeSemantic proximity Read

Automated extraction of primary cilia-based biomarkers reveals ageing of cellsSemantic proximity Read

Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome.Semantic proximity Read

Novel fibrillar structure in the inversin compartment of primary cilia revealed by 3D single-molecule superresolution microscopy.Semantic proximity Read

Superresolution microscopy reveals photoreceptor-specific subciliary location and function of Cep290Semantic proximity Read

The molecular structure of primary cilia revealed by cryo-electron tomographySemantic proximity Read

3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communicationSemantic proximity Read

Centriole and transition zone structures in photoreceptor cilia revealed by cryo-electron tomographySemantic proximity Read

Imaging intraflagellar transport in mammalian primary cilia.Semantic proximity Read