Article

Direct influence of BMPR2 mutations on cytokine patterns and biomarker effectiveness in pulmonary arterial hypertension

2021-05-07

Abstract excerpt

<h4>Background</h4> Pulmonary arterial hypertension (PAH) covers a range of life-limiting illnesses characterized by increased pulmonary arterial pressures leading to right heart failure and death, if untreated. 15-25% of patients have genetic mutations, the most common affecting bone morphogenetic protein receptor type 2 ( BMPR2) . The aim was to define an inflammatory cytokine profile in BMPR2 -mutation positive...

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Literature Corpus work: 49e6714a-1422-51da-b96e-ae6e805ff765
DOI: 10.1101/2021.05.05.21253970

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