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The unique pattern of mannose-capped lipoarabinomannan expression in <i>Mycobacterium tuberculosis</i> with different drug resistant profiles following isoniazid stress

2021-10-20

Abstract excerpt

Tuberculosis (TB) is a global health problem caused by Mycobacterium tuberculosis (MTB) infection. The main problem of TB treatment is the emergence of drug resistance, which can occur by inappropriate of antibiotic used. Isoniazid (INH) is the first-line anti-TB drug that inhibits mycolic acid synthesis, an important part of the mycobacterial cell wall. Mannose-capped lipoarabinomannan (ManLAM) is an essential c...

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Literature Corpus work
49e5bbf2-6f59-5e0c-811c-604258fbd438
DOI
10.1101/2021.10.20.465078
Open publication

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The unique pattern of mannose-capped lipoarabinomannan expression in <i>Mycobacterium tuberculosis</i> with different drug resistant profiles following isoniazid stressDOI 10.1101/2021.10.20.465078
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