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Large Scale Purification and Characterization of A21 Deamidated Variant-Most Prominent Post Translational Modification (PTM) for Insulins Which Is Widely Observed in Insulins Pharmaceutical Manufacturing

2020-12-09

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe rapid growth of global diabetic population attracts the large scale manufacturing of insulin and analogues to meet the unmet demand. Biopharmaceutical development demands appropriate understanding of product variant, which are formed due to post-translational modification. Deamidation is the most common post‐translational modification occurring in insulins and insulin anal...

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Literature Corpus work
49a9b114-b9d9-5a9d-820a-f518e90a1c47
DOI
10.21203/rs.3.rs-122061/v1
Open publication

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Large Scale Purification and Characterization of A21 Deamidated Variant-Most Prominent Post Translational Modification (PTM) for Insulins Which Is Widely Observed in Insulins Pharmaceutical ManufacturingDOI 10.21203/rs.3.rs-122061/v1
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