Article

Tubular aryl hydrocarbon receptor upregulates EZH2 to promote cell senescence in cisplatin-induced acute kidney injury

2022-08-01

Abstract excerpt

<title>Abstract</title> <p>Acute kidney injury (AKI) is one of the serious clinical syndromes with high morbidity and mortality. Despite substantial progress in understanding of AKI mechanism, no drug therapy is available for treatment or prevention. In this study, we identified that a ligand-activated transcription factor aryl hydrocarbon receptor (AhR) was highly expressed in the kidneys of cisplatin-induced AK...

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Literature Corpus work: 498f8b87-17c1-5465-93e1-a58a014e1ba4
DOI: 10.21203/rs.3.rs-1848869/v1

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