Article

Unveiling the Silent Antiviral Effectors Fighting Against COVID-19

2020-07-09

Abstract excerpt

The host cell receptors and associated anti-viral genes mediating SARS-CoV-2 infections are still elusive. Here, we show that COVID-19 patients compared with healthy donors, display discrepancies regarding up-regulation of ACE2 and TMPRSS2. Further, we have screened in these samples key players associated with the antiviral response: <i>MX1, IRF3, HMOX1</i> and <i>ADAM17</i>. Strikingly, results show that COVID-19...

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Literature Corpus work: 49740a8e-3d41-54e9-975c-cad95a1ea7d3
DOI: 10.2139/ssrn.3640827

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