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Targeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage

2020-05-05

Abstract excerpt

DNA methylation analysis is increasingly used in stress research. Available methods are expensive, laborious and often limited by either the analysis of short CpG stretches or low assay sensitivity. Here, we present a cost-efficient next generation sequencing-based strategy for the simultaneous investigation of multiple candidate genes in large cohorts. To illustrate the method, we present analysis of four candida...

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Literature Corpus work
4959e72b-c1dc-5d75-90ee-e739951ff8a1
DOI
10.1101/2020.05.05.078386
Open publication

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Targeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverageDOI 10.1101/2020.05.05.078386
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