Article
SFXN-1.2-CX32 complex selectively recruits UNC-104 to neuronal mitochondria
2026-01-07
Abstract excerpt
<title>Abstract</title> <p> Various neurological diseases are linked to changes in mitochondrial trafficking in axons. Thus, it is crucial to understand how dynamics of mitochondria are regulated on the molecular level. From a candidate screen, we identified SFXN-1.2 to regulate both morphologies as well as dynamics of mitochondria. SFXN-1.2 is an ortholog of human Sideroflexin 1/3 associated with Alzheimer's di...
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Identifiers and source
- Literature Corpus work
- 490d87ac-1e44-569a-9504-e2a022a6a9f6
- DOI
- 10.21203/rs.3.rs-2953132/v3
