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Article

Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A.

Experimental neurology - 1 Aug 2009

Cartoni Romain, Martinou Jean-Claude

Abstract excerpt

Charcot-Marie-Tooth disease (CMT) is the most common form of hereditary peripheral neuropathy. The main axonal form of CMT, CMT2A, preferentially affects peripheral neurons with the longest neurites. CMT2A has been recently linked to mutations in the mitofusin 2 (Mfn2) gene. Mfn2 participates in mitochondrial fusion a process that together with mitochondrial fission, contributes to mitochondrial morphology. Many...

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PMID: 19427854
DOI: 10.1016/j.expneurol.2009.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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