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Article

MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives.

Journal of the neurological sciences - 15 Sept 2015

Stuppia Giulia, Rizzo Federica, Riboldi Giulietta, Del Bo Roberto, Nizzardo Monica, Simone Chiara, Comi Giacomo P, Bresolin Nereo, Corti Stefania

Abstract excerpt

Mitofusin 2 (MFN2) is a GTPase dynamin-like protein of the outer mitochondrial membrane, encoded in the nuclear genome by the MFN2 gene located on the short (p) arm of chromosome 1. MFN2 protein is involved in several intracellular pathways, but is mainly involved in a network that has an essential role in several mitochondrial functions, including fusion, axonal transport, interorganellar communication and...

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Source

Identifiers

PMID: 26143526
DOI: 10.1016/j.jns.2015.05.033

Genes

MFN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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