Article

Genetic liability for anxiety associates with treatment response to the monoamine stabilizer OSU6162 in alcohol dependence

2024-03-15

Abstract excerpt

OSU6162, a monoamine stabilizer, has demonstrated efficacy in reducing alcohol and anxiety-related behaviors in preclinical settings. In a previous randomized, double-blind, placebo-controlled trial involving patients with alcohol dependence (AD), we found that OSU6162 significantly reduced craving for alcohol, but did not alter drinking behaviors. In the present study, we explored the hypothesis that genetic pred...

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Literature Corpus work: 49097c21-f94f-53e6-accf-4b3db022517e
DOI: 10.1101/2024.03.11.24304098

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