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Article

HIV-1 co-receptor usage and variable loop contact impacts V3 loop bnAb susceptibility

2019-03-05

Abstract excerpt

<h4>ABSTRACT</h4> In clinical trials, HIV-1 broadly neutralizing antibodies (bnAbs) effectively lower plasma viremia and delay virus reemergence after antiretroviral treatment is stopped among infected individuals that have undetectable virus levels. Presence of less neutralization susceptible strains prior to treatment, however, decreases the efficacy of these antibody-based treatments. The HIV-1 envelope glycop...

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Literature Corpus work
48df8394-3319-54b5-ad2e-896515491136
DOI
10.1101/568469
Open publication

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HIV-1 co-receptor usage and variable loop contact impacts V3 loop bnAb susceptibilityDOI 10.1101/568469
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