Article

IL-5 blockade restores the bronchial epithelium and attenuates airway remodelling in severe asthma

2026-07-24

Abstract excerpt

<h4>Rationale</h4> Airway remodelling (AR) contributes to airflow limitation and poor symptom control in severe asthma. While anti-IL-5 therapy improves clinical outcomes in severe asthma, the cellular and molecular mechanisms underlying its effects on AR remain incompletely understood. <h4>Objectives.</h4> To determine whether IL-5 blockade directly modulates airway epithelial biology and contributes to attenua...

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Literature Corpus work: 48d7014e-13dd-5d04-81c2-750b6a5b1b0c
DOI: 10.64898/2026.07.22.26358464

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