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Article

Decoding human cytomegalovirus.

Science (New York, N.Y.) - 23 Nov 2012

Stern-Ginossar Noam, Weisburd Ben, Michalski Annette, Le Vu Thuy Khanh, Hein Marco Y, Huang Sheng-Xiong, Ma Ming, Shen Ben, Qian Shu-Bing, Hengel Hartmut, Mann Matthias, Ingolia Nicholas T, Weissman Jonathan S

Abstract excerpt

The human cytomegalovirus (HCMV) genome was sequenced 20 years ago. However, like those of other complex viruses, our understanding of its protein coding potential is far from complete. We used ribosome profiling and transcript analysis to experimentally define the HCMV translation products and follow their temporal expression. We identified hundreds of previously unidentified open reading frames and confirmed a...

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Identifiers

PMID: 23180859
DOI: 10.1126/science.1227919
PMCID: PMC3817102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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