Article

Multi-omics reveals principles of gene regulation and pervasive non-productive transcription in the human cytomegalovirus genome

2022-01-07

Abstract excerpt

For decades, human cytomegalovirus (HCMV) was thought to express ≈200 viral proteins during lytic infection. In recent years, systems biology approaches uncovered hundreds of additional viral gene products and suggested thousands of viral sites of transcription initiation. Despite all available data, the molecular mechanisms of HCMV gene regulation remain poorly understood. Here, we provide a unifying model of pro...

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Literature Corpus work: db2f9203-7d01-5f69-8dd4-dec8bd8879a2
DOI: 10.1101/2022.01.07.472583

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