Article

Whole genome sequencing identifies putative associations between genomic polymorphisms and clinical response to the antiepileptic drug <i>levetiracetam</i>

2019-09-27

Abstract excerpt

<h4>ABSTRACT</h4> In the context of pharmacogenomics, whole genome sequencing provides a powerful approach for identifying correlations between response variability to specific drugs and genomic polymorphisms in a population, in an unbiased manner. In this study, we employed whole genome sequencing of DNA samples from patients showing extreme response (n=72) and non-response (n=27) to the antiepileptic drug leveti...

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Literature Corpus work: 48c06a8d-db24-5e27-93f6-ef2ee87bef5d
DOI: 10.1101/19007674

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