Article
A translational multimodal machine-learning prototype predicting valproate response in epilepsy treatment
2025-08-27
Abstract excerpt
Epilepsy affects around 1% of the global population and often requires long-term treatment with antiseizure medications (ASMs). However, the current treatment strategy is based on clinical acumen and trial and error, resulting in only about 50% of patients remaining seizure-free for at least 12 months with first-line ASMs. Valproic acid (VPA) is a commonly prescribed first-line ASM, yet <50% of patients experience...
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Identifiers and source
- Literature Corpus work
- 2bd05d9c-4c1a-5fdf-b5e1-89ff05b1d20a
- DOI
- 10.1101/2025.08.21.25332294