Back to search

Article

<i>In vitro</i> phenotypic and transcriptomic variation in <i>Neisseria musculi</i> morphotypes correlate with colonization variability and persistence <i>in vivo</i>

2022-02-04

Abstract excerpt

<h4>ABSTRACT</h4> Asymptomatic colonization of the upper respiratory tract is a common trait of the two human restricted pathogens, Neisseria gonorrhoeae and Neisseria meningitidis. In vivo models of pathogenic neisserial infections are heterologous systems that permit short-term colonization but do not fully recapitulate infections in humans. Studying Neisseria musculi (Nmus), an oral commensal, in laboratory...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
48bd4a66-710d-5755-8b11-7b67741125ad
DOI
10.1101/2022.02.03.479073
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>In vitro</i> phenotypic and transcriptomic variation in <i>Neisseria musculi</i> morphotypes correlate with colonization variability and persistence <i>in vivo</i>DOI 10.1101/2022.02.03.479073
Unveiling the Immune Dynamics of Neisseria Persistent Oral Colonization: A Roadmap for Innovative Vaccine StrategiesSemantic proximity
Neisseria genes required for persistence identified via in vivo screening of a transposon mutant librarySemantic proximity
A Natural Mouse Model for Neisseria ColonizationSemantic proximity
Phase variable colony morphotypes of <i>Clostridioides difficile</i> elicit distinct host responses during acute infectionSemantic proximity
Unraveling Neisseria meningitidis pathogenesis: from functional genomics to experimental modelsSemantic proximity
Genetic diversity of Collaborative Cross mice enables the establishment of a novel <i>Chlamydia muridarum</i> female genital tract infection modelSemantic proximity
A murine model of adult gastrointestinal colonization by Group B <i>Streptococcus</i>Semantic proximity
Strain-level differences in <i>Gardnerella</i> urinary tract persistence and pathogenesis are consistent with comparative phylogenomic analysesSemantic proximity
Influenza A Virus Coinfection Alters <i>Streptococcus pneumoniae</i> Gene Expression during Upper Respiratory Tract ColonizationSemantic proximity
Phase variable colony morphotypes of Clostridioides difficile elicit distinct host responses during acute infection.Semantic proximity
Comparative Genome Sequencing Reveals Within-Host Genetic Changes in Neisseria meningitidis during Invasive Disease.Semantic proximity
Assessment of Antimicrobial Therapy in Eradicating <i>Chlamydia muridarum</i> in Research Mice: Immune Status and its Impact on OutcomesSemantic proximity
Select a neighboring publication to make it the new centre.