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Assessment of Antimicrobial Therapy in Eradicating <i>Chlamydia muridarum</i> in Research Mice: Immune Status and its Impact on Outcomes

2024-06-29

Abstract excerpt

Chlamydia muridarum (Cm) is a moderately prevalent, gram-negative, intracellular bacterium that affects laboratory mice, causing subclinical to severe disease, depending on the host’s immune status. The effectiveness of various antibiotic regimens aimed at eradicating Cm in both immunodeficient and immunocompetent laboratory mice was evaluated. NSG mice were cohoused with Cm-shedding BALB/cJ mice for 14 days to si...

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Literature Corpus work
8aa0bb3f-698f-5656-bb6d-0b4396150b56
DOI
10.1101/2024.06.28.600682
Open publication

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Assessment of Antimicrobial Therapy in Eradicating <i>Chlamydia muridarum</i> in Research Mice: Immune Status and its Impact on OutcomesDOI 10.1101/2024.06.28.600682
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