Article
Molecular modeling and description of a newly characterized activating mutation of the EGFR gene in non-small cell lung cancer.
Diagnostic pathology - 22 Oct 2012
Otto Claudia, Csanadi Agnes, Fisch Paul, Werner Martin, Kayser Gian
Abstract excerpt
Lung cancer is the leading cause of death among malignant diseases in humans worldwide. In the last decade development of new targeted drugs for the treatment of non-small cell lung cancer proved to be a promising approach to prolong the otherwise very poor prognosis of patients with advanced UICC stages. Epidermal growth factor receptor (EGFR) has been in the focus of this lung cancer science and specific...
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