Back to search

Article

Accelerated vaccine induction of IgM neutralising antibody enables vaccine protection against same day lethal influenza virus challenge

2021-02-18

Abstract excerpt

<h4>ABSTRACT</h4> Novel influenza strains to which humans have no pre-existing immunity can trigger global pandemics without warning. Current pandemic vaccines typically require two doses and up to 6 weeks to induce protective immunity. In addition, to their role in increasing vaccine-induced immune response, adjuvants may also play a part in reducing the time between immunization and vaccine protection, although...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
489e5482-7898-5a73-9b54-3f30663bb9fb
DOI
10.1101/2021.02.17.431751
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Accelerated vaccine induction of IgM neutralising antibody enables vaccine protection against same day lethal influenza virus challengeDOI 10.1101/2021.02.17.431751
Delta Inulin Adjuvant Enhances Plasmablast Generation, Expression of Activation-Induced Cytidine Deaminase and B-Cell Affinity Maturation in Human Subjects Receiving Seasonal Influenza Vaccine.Semantic proximity
Influenza Management Prospects of Passive ImmunotherapySemantic proximity
Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels.Semantic proximity
Modernizing the original influenza vaccine to enhance protective antibody responses against neuraminidase antigensSemantic proximity
Poly-γ-Glutamic Acid/Alum Adjuvanted pH1N1 Vaccine-Immunized Aged Mice Exhibit a Significant Increase In Vaccine Efficacy With a Decrease in Age-Associated CD8+ T Cell Proportion in SplenocytesSemantic proximity
Sub-neutralizing concentrations of Zika virus IgM monoclonal antibodies reduce IgG-mediated antibody-dependent enhancement of infectivitySemantic proximity
A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virusSemantic proximity
A single oral immunization with a replication-competent adenovirus-vectored vaccine protects mice from influenza respiratory infectionSemantic proximity
Pre-existing Immunity to H1N1 Influenza Virus Improves Antibody Response to Vaccination through Germinal Center RegulationSemantic proximity
Sequential Aerosol and Oral Immunization with a Bivalent H9N2/H5N2 Vaccine Protects Against H5N1 and H9N2 Avian Influenza ChallengesSemantic proximity
Immunity induced by vaccination with recombinant influenza B virus neuraminidase protein breaks viral transmission chains in guinea pigs in an exposure intensity-dependent mannerSemantic proximity
Intranasal Immunization with Recombinant HA and Mast Cell Activator C48/80 Elicits Protective Immunity against 2009 Pandemic H1N1 Influenza in MiceSemantic proximity
Select a neighboring publication to make it the new centre.