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Sequential Aerosol and Oral Immunization with a Bivalent H9N2/H5N2 Vaccine Protects Against H5N1 and H9N2 Avian Influenza Challenges

2025-09-02

Abstract excerpt

<title>Abstract</title> <p>Avian influenza continues to be a major threat to poultry and public health. This study investigated the efficacy of a bivalent H9N2/H5N2 modified live virus (MLV) vaccine delivered through a sequential aerosol priming and drinking water boosting strategy in chickens. We hypothesized that this dual-route vaccination strategy would induce robust protective immunity against both low patho...

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Literature Corpus work
1ae289c9-9851-5508-a5d0-e3a3f7020bc6
DOI
10.21203/rs.3.rs-7402596/v1
Open publication

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Sequential Aerosol and Oral Immunization with a Bivalent H9N2/H5N2 Vaccine Protects Against H5N1 and H9N2 Avian Influenza ChallengesDOI 10.21203/rs.3.rs-7402596/v1
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