Article

Benchmarking zero-shot single-cell foundation model embeddings for cellular dynamics reconstruction

2026-03-12

Abstract excerpt

Reconstructing cellular trajectories from time-resolved single-cell transcriptomics is fundamental to understanding processes from embryonic development to cancer progression. While single-cell foundation models (scFMs) promise universal biological representations through large-scale pretraining, their capacity to capture the non-linear dynamics governing cell-fate decisions remains uncharacterized. Here we system...

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Literature Corpus work: 48854a75-b904-5efe-be97-9dff4ee836a5
DOI: 10.64898/2026.03.10.710748

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