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Multi-omics Analysis Reveals Prognostic Biomarker Candidates for Calcific Uremic Arteriolopathy Patients Treated with Stem Cells

2024-12-18

Abstract excerpt

Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is an orphan disease without proven therapies, we rescued it with human amnion-derived mesenchymal stem cells (hAMSCs). In a discovery cohort of 10 uremic patients and 3 CUA patients, plasma proteomic analysis showed core differentially expressed proteins (DEPs) Thrombospondin 1 (THBS1) and Latent transforming growth factor (TGF)-β binding protein...

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Literature Corpus work: 485c2f76-8c03-5fd6-be75-941c1ae61cdd
DOI: 10.1101/2024.12.11.24309074

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