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Multi-Omics Exploration of the Role of PTGS2 as a Hub Gene in Ferroptosis Within the Artery of Takayasu Arteritis

1 Nov 2024

Abstract excerpt

Introduction: Takayasu arteritis (TAK) is an autoimmune disease affecting the aorta and its branches. Despite anti-inflammatory treatments, some patients require surgical vascular reconstruction due to rapid disease progression. The mechanisms behind persistent inflammation are unclear due to a lack of arterial samples. This study explores ferroptosis in TAK using high-throughput and single-cell transcriptomics....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39588139
DOI: 10.2147/jir.s478413

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