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Article

Riemannian geometry and statistical modeling correct for batch effects and control false discoveries in single-cell surface protein count data from CITE-seq

2020-04-29

Abstract excerpt

Recent advances in next generation sequencing-based single-cell technologies have allowed high-throughput quantitative detection of cell-surface proteins along with the transcriptome in individual cells, extending our understanding of the heterogeneity of cell populations in diverse tissues that are in different diseased states or under different experimental conditions. Count data of surface proteins from the cel...

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Literature Corpus work
47b9a3e4-da3f-536e-a47d-323c763f429f
DOI
10.1101/2020.04.28.067306
Open publication

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Riemannian geometry and statistical modeling correct for batch effects and control false discoveries in single-cell surface protein count data from CITE-seqDOI 10.1101/2020.04.28.067306
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