Article
A systems genetics approach identifies roles for proteasome factors in heart development and congenital heart defects
2025-01-21
Abstract excerpt
Congenital heart defects (CHDs) occur in about 1% of live births and are the leading cause of infant death due to birth defects. While there have been remarkable efforts to pursue large-scale whole-exome and genome sequencing studies on CHD patient cohorts, it is estimated that these approaches have thus far accounted for only about 50% of the genetic contribution to CHDs. We sought to take a new approach to ident...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 476ccc3c-8d21-54c1-9bce-7ecee0bce73d
- DOI
- 10.1101/2025.01.16.633339