Article

Z-Flipons conserved between human and mouse are associated with increased transcription initiation rates

2023-11-03

Abstract excerpt

A long-standing question concerns the role of Z-DNA in transcription. Here we use a deep learning approach based on the published DeepZ algorithm that predicts Z-flipons based on DNA sequence, structural properties of nucleotides and omics data. We examined Z-flipons that are conserved between human and mouse genomes after generating whole-genome Z-flipons maps by training DeepZ on ChIP-seq Z-DNA data, then overla...

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Literature Corpus work: 471bf7f4-26a2-5272-be31-45334c9e7beb
DOI: 10.1101/2023.10.31.564984

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