Article
Cinnamic aldehyde induces apoptosis of breast cancer cells via STAT3/cMyc pathway
2022-09-23
Abstract excerpt
<title>Abstract</title> <p>Signal transducer and activator of transcription 3 (STAT3) is known to be activated in numerous cancer types, including more than 40% of breast cancers. STAT3 ’s downstream gene cMyc serves as an important target in cancer treatment. However, the clinical availability of small-molecule inhibitors that can target cMyc are lacking.Cinnamic aldehyde (CA) has been reported to inhibit the pr...
Topics
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- Bioactive Compounds and Antitumor Agents
- Cancer Cells and Metastasis
- Computational Drug Discovery Methods
- Cytokine Signaling Pathways and Interactions
- Fungal Biology and Applications
- Genomics, phytochemicals, and oxidative stress
- Natural Antidiabetic Agents Studies
- Pharmacological Effects of Medicinal Plants
Identifiers and source
- Literature Corpus work
- 5ae991c2-a129-503d-b614-e494b0ea947d
- DOI
- 10.21203/rs.3.rs-2058567/v1
