Article

Calicivirus VP2 forms a portal to mediate endosome escape

2018-08-23

Abstract excerpt

To initiate the infectious process, many viruses enter their host cells by triggering endocytosis following receptor engagement. The mechanism by which non-enveloped viruses, such as the caliciviruses, escape the endosome is however poorly understood. The Caliciviridae include many important human and animal pathogens, most notably norovirus, the cause of winter vomiting disease. Here we show that VP2, a minor ca...

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Literature Corpus work: 46e1a8ca-a800-5007-8db6-c0e3db4739de
DOI: 10.1101/397901

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