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Single Cell Transcriptomics-guided Antisense Treatment Improves Endoderm Differentiation of iPSCs

2020-05-14

Abstract excerpt

Directed differentiation of induced pluripotent stem cells (iPSCs) enables the production of relevant cell types for studies of human biology, disease-modeling, and efforts towards cellular therapy and transplantation. However, the low yield and purity of desired cell types can limit the utility of this approach. Enhancing differentiation purity can require extensive optimization of morphogen treatments, and this...

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Literature Corpus work
46d2b8a4-3c9a-5d63-a170-da5c291bfc5c
DOI
10.1101/2020.05.13.092593
Open publication

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Single Cell Transcriptomics-guided Antisense Treatment Improves Endoderm Differentiation of iPSCsDOI 10.1101/2020.05.13.092593
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