Identification of Differentially Expressed Genes Related to UFMylation Modifications in Periodontitis: Integrated Insights from Transcriptomics and Clinical Experiments

Abstract excerpt

<title>Abstract</title> <p> Background Periodontitis is a globally prevalent chronic inflammatory oral disease driven by oral microbiota dysbiosis, which triggers abnormal host immune responses and irreversible damage to periodontal supporting structures. UFMylation, a key post-translational modification involved in regulating protein function and inflammatory processes, has been linked to various inflammatory...

Topics

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• Bone and Dental Protein Studies
• Bone Metabolism and Diseases
• Ferroptosis and cancer prognosis
• Machine Learning in Bioinformatics
• Oral Health Pathology and Treatment
• Oral microbiology and periodontitis research
• Rheumatoid Arthritis Research and Therapies
• Salivary Gland Disorders and Functions

Identifiers and source

Literature Corpus work

fa352a20-1322-5aac-a1ae-29eed8bcc563

DOI

10.21203/rs.3.rs-10177665/v1