Article

Identification of a shared persistence program in triple-negative breast cancer across treatments and patients

2025-03-18

Abstract excerpt

Acquisition of resistance to anti-cancer therapies is a multistep process, which initiates with the survival of drug persister cells. Understanding the mechanisms driving the emergence of persister cells remains challenging, primarily because of their limited accessibility in patients. Here, using mouse models to isolate persister cells from patient tumors, we determine the identity features of persister cells fro...

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Literature Corpus work: 45e842ce-323d-5478-9f12-9c7264eb344d
DOI: 10.1101/2025.03.17.643634

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