Transcription factors-related molecular subtypes and risk prognostic model: exploring the immunogenicity landscape and potential drug targets in hepatocellular carcinoma

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer, with a high mortality rate and poor prognosis. Mutated or dysregulated transcription factors (TFs) are significantly associated with carcinogenesis. The aim of this study was to develop a TF-related prognostic risk model to predict the prognosis and guide the treatment of HCC patients. METHODS: RNA sequencing data were obtained...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ferroptosis and cancer prognosis
• Share to FOXO transcription factor regulation
• Share to NF-κB Signaling Pathways