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Article

Design of the Oligonucleotide Carriers: Importance of Polyamine Chain Length

2018-10-23

Abstract excerpt

Amine containing polymers are extensively studied as special carriers for short-chain RNA (13–25 nucleotides) which are applied as gene silencing agent in gene therapy of various diseases including cancer. Elaboration of the oligonucleotide carriers requires knowledge about peculiarities of oligonucleotide - polymeric amine interaction. Critical length of the interacting chains is the important parameter whi...

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Identifiers and source

Literature Corpus work
45d341df-bc20-5ebd-b43e-ff103c035685
DOI
10.20944/preprints201810.0515.v1
Open publication

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Design of the Oligonucleotide Carriers: Importance of Polyamine Chain LengthDOI 10.20944/preprints201810.0515.v1
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