Article

Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina

2024-12-29

Abstract excerpt

Most genetic risk variants linked to ocular diseases are non-protein coding and presumably contribute to disease through dysregulation of gene expression, however, deeper understanding of their mechanisms of action has been impeded by an incomplete annotation of the transcriptional regulatory elements across different retinal cell types. To address this knowledge gap, we carried out single-cell multiomics assays t...

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Literature Corpus work: c6dea09f-302f-54a4-bd1f-7544942c4bea
DOI: 10.1101/2024.12.28.630634

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