Article

Caecal dysfunction in the NL3 <sup>R451C</sup> mouse model of autism

2022-06-16

Abstract excerpt

The mouse caecum is a pouch-like structure that is anatomically similar to the human appendix and is hypothesised to serve as a reservoir for commensal bacteria. The gastrointestinal tract is also home to the largest immunological organ of the body and the enteric nervous system (ENS), which regulates gut motility and secretion. The caecum is therefore an ideal location to study neuro-immune-microbe interactions i...

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Literature Corpus work: 45780040-c20f-5fa3-84c3-167a104116c5
DOI: 10.1101/2022.06.15.494637

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