Article
The zebrafish mutant lessen: an experimental model for congenital enteric neuropathies.
Neurogastroenterology and motility - 1 Mar 2016
Uyttebroek L, Shepherd I T, Vanden Berghe P, Hubens G, Timmermans J-P, Van Nassauw L
Abstract excerpt
BACKGROUND: Congenital enteric neuropathies of the distal intestine (CEN) are characterized by the partial or complete absence of enteric neurons. Over the last decade, zebrafish has emerged as a leading model organism in experimental research. Our aim was to demonstrate that the mutant zebrafish, lessen, expressing CEN characteristics, is an equally valuable animal model alongside mammalian models for CEN, by...
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