Article

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility

2024-05-29

Abstract excerpt

<h4>ABSTRACT</h4> The comorbidity of autism spectrum disorders and severe gastrointestinal symptoms is well-established, yet the molecular underpinnings remain unknown. The identification of high-confidence large-effect autism risk genes offers the opportunity to identify convergent, underlying biology by studying these genes in the context of the gastrointestinal system. Here we show that the expression of these...

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Literature Corpus work: 756e75c4-4961-5140-bf9a-db961149bf93
DOI: 10.1101/2024.05.28.593642

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