Article

Retracing Human Genetic Histories and Natural Selection Using Precise Local Ancestry Inference

2023-09-13

Abstract excerpt

In an increasingly diverse world, including admixed individuals in genomic studies is imperative for equity and portability. A crucial first step is precise local ancestry inference (LAI). We have developed Orchestra, a LAI model with unprecedented accuracy, and trained on over 10,000 single-origin individuals from 35 worldwide populations. We employed Orchestra to delve into genetic relationships and demographic...

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Literature Corpus work: 456f748d-55c1-562e-91e7-7aee29fe8b8e
DOI: 10.1101/2023.09.11.557177

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