Back to search

Article

Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19

2023-08-28

Abstract excerpt

The role of host genetic factors in COVID-19 outcomes remains unclear despite of various genome-wide association studies (GWAS). We annotate all significant variants and those variants in high LD (R 2 > 0.8) from the COVID-19 Host Genetics Initiative (HGI) and identify risk genes by recognizing genes intolerant nonsynonymous mutations in coding regions and genes associated with cis-expression quantitative trait lo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
456279ed-982d-5f19-9d58-f66c9994e8ad
DOI
10.21203/rs.3.rs-3281161/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19DOI 10.21203/rs.3.rs-3281161/v1
Select a neighboring publication to make it the new centre.