Article

Secondary analysis of transcriptomes of SARS-CoV-2 infection models to characterize COVID-19

2020-08-28

Abstract excerpt

<h4>ABSTRACT</h4> Knowledge about the molecular mechanisms driving COVID-19 pathophysiology and outcomes is still limited. To learn more about COVID-19 pathophysiology we performed secondary analyses of transcriptomic data from two in vitro (Calu-3 and Vero E6 cells) and one in vivo (Ad5-hACE2-sensitized mice) models of SARS-CoV-2 infection. We found 1467 conserved differentially expressed host genes (different...

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Literature Corpus work: afd6ac23-18cc-5dd2-8479-3567951e9e2e
DOI: 10.1101/2020.08.27.270835

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