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Article

MINOES: a new approach to select a representative ensemble of structures in NMR studies of (partially) unfolded states. Application to Delta25-PYP.

Proteins - 1 Mar 2009

Krzeminski Mickaël, Fuentes Gloria, Boelens Rolf, Bonvin Alexandre M J J

Abstract excerpt

In nature, some proteins partially unfold under specific environmental conditions. These unfolded states typically consist of a large ensemble of conformations; their proper description is therefore a challenging problem. NMR spectroscopy is particularly well suited for this task: information on conformational preferences can be derived, for example, from chemical shifts or residual dipolar couplings. This...

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PMID: 18704926
DOI: 10.1002/prot.22197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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