Article

Tumor-tumor Cell Fusion Hybrids Obtained by the Modified PHA-DMSO-PEG Method Promote Temozolomide Resistance in Glioma

2021-04-07

Abstract excerpt

<h4>Background: </h4> Cell fusion and the subsequent aneuploidy are commonly observed in different kinds of tumor. In glioma, cell fusion and the number of the polyploid giant cells were found to be augmented with the tumor grades (WHO Ⅰ-Ⅳ) and closely related to poor prognosis. Phytohemagglutinin (PHA) holds an ability to induce cell-cell membrane contact and accelerates the cell fusion process mediated by the fu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 455f89b4-e4bb-5643-93bf-536926ff4349
DOI: 10.21203/rs.3.rs-396256/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Tumor-tumor Cell Fusion Hybrids Obtained by the Modified PHA-DMSO-PEG Method Promote Temozolomide Resistance in GliomaDOI 10.21203/rs.3.rs-396256/v1Read

Hybrid Formation and Fusion of Cancer Cells In Vitro and In VivoSemantic proximity Read

Fusion between tumor cells enhances melanoma metastatic potential.Semantic proximity Read

Cell Fusion is a Potent Inducer of Aneuploidy and Drug Resistance in Tumor Cell/ Normal Cell HybridsSemantic proximity Read

Cell-Cell Fusion and the Roads to Novel Properties of Tumor Hybrid Cells.Semantic proximity Read

Glioma Cells Achieve Malignant Progression by Fusion with Macrophages to Gain High SLC7A5 ExpressionSemantic proximity Read

Roles of cell fusion, hybridization and polyploid cell formation in cancer metastasisSemantic proximity Read

Extracellular Events Involved in Cancer Cell–Cell FusionSemantic proximity Read

Cancer cell fusion: a potential target to tackle drug-resistant and metastatic cancer cellsSemantic proximity Read

Intrinsic signalling factors associated with cancer cell-cell fusionSemantic proximity Read

Cell Fusion as a Hidden Force in Tumor ProgressionSemantic proximity Read

Cancer Cell Fusion and Post-Hybrid Selection Process (PHSP)Semantic proximity Read

Linking Unfolded Protein Response to Ovarian Cancer Cell FusionSemantic proximity Read