Article

An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

2024-11-21

Abstract excerpt

<title>Abstract</title> <p>Coronaviruses have caused three major endemics in the past two decades. Alarmingly, recent identification of novel zoonotic coronaviruses that caused human infections suggests the risk of future coronavirus outbreak caused by spillover infection from animal reservoirs remains high<sup>1,2</sup>. Therefore, development of novel therapeutic options with broad-spectrum anti-coronavirus act...

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Literature Corpus work: 4559e3e3-86bc-5802-83fb-66928007a745
DOI: 10.21203/rs.3.rs-5454588/v1

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