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Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential

2023-06-28

Abstract excerpt

Despite the wide availability of several safe and effective vaccines that can prevent severe COVID-19 disease, the emergence of SARS-CoV-2 variants of concern (VOC) that can partially evade vaccine immunity remains a global health concern. In addition, the emergence of highly mutated and neutralization-resistant SARS-CoV-2 VOCs such as BA.1 and BA.5 that can partially or fully evade ( 1 ) many therapeutic monoclo...

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Literature Corpus work
65da6383-1ab1-5e04-af94-7006381e7d45
DOI
10.1101/2023.06.27.546784
Open publication

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Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potentialDOI 10.1101/2023.06.27.546784
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