Back to search

Article

Cross-Protection Induced by Highly Conserved Human B, CD4 <sup>+,</sup> and CD8 <sup>+</sup> T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multiple SARS-CoV-2 Variants of Concern

2023-05-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The Coronavirus disease 2019 (COVID-19) pandemic has created one of the largest global health crises in almost a century. Although the current rate of SARS-CoV-2 infections has decreased significantly; the long-term outlook of COVID-19 remains a serious cause of high death worldwide; with the mortality rate still surpassing even the worst mortality rates recorded for the inf...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
dc81fbf8-5e35-5c6d-9512-d6b04e7093fb
DOI
10.1101/2023.05.24.541850
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cross-Protection Induced by Highly Conserved Human B, CD4 <sup>+,</sup> and CD8 <sup>+</sup> T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multiple SARS-CoV-2 Variants of ConcernDOI 10.1101/2023.05.24.541850
A Multi-Antigen Broad-Spectrum Coronavirus Vaccine Induces Potent and Durable Cross- Protection Against Infection and Disease Caused by Multiple SARS-CoV-2 VariantsSemantic proximity
Genome-Wide Asymptomatic B-Cell, CD4 <sup>+</sup> and CD8 <sup>+</sup> T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus VaccinesSemantic proximity
A Pan-Beta-Coronavirus Vaccine Bearing Conserved and Asymptomatic B- and T-Cell Epitopes Protect Against Highly Pathogenic Delta and Highly Transmissible Omicron SARS-CoV-2 Variants of ConcernSemantic proximity
Dynamics of Spike-Specific Neutralizing Antibodies Across Five-Year Emerging SARS-CoV-2 Variants of Concern Reveal Conserved Epitopes that Protect Against Severe COVID-19Semantic proximity
Tissue-resident memory CD8 T-cell responses elicited by a single injection of a multi-target COVID-19 vaccineSemantic proximity
Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus VaccinesSemantic proximity
Baculoviral COVID-19 Delta DNA vaccine cross-protects against SARS-CoV2 variants in K18-ACE2 transgenic miceSemantic proximity
Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus VaccinesSemantic proximity
Bioinformatic analysis of shared B and T cell epitopes amongst relevant coronaviruses to human health: Is there cross-protection?Semantic proximity
A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster ModelSemantic proximity
The T cell epitope landscape of SARS-CoV-2 variants of concernSemantic proximity
Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ SubjectsSemantic proximity
Select a neighboring publication to make it the new centre.